Osteoactivin antibody (AA 31-260)

Catalog No. ABIN1845730

Product Details anti-Osteoactivin Antibody

Target: Osteoactivin (GPNMB)

Binding Specificity: AA 31-260

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Osteoactivin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for Osteoactivin

Target: Osteoactivin (GPNMB)

Alternative Name: GPNMB (GPNMB Products)

Synonyms: HGFIN antibody, NMB antibody, DC-HIL antibody, Dchil antibody, ipd antibody, glycoprotein nmb antibody, glycoprotein (transmembrane) nmb antibody, glycoprotein nmb L homeolog antibody, Gpnmb antibody, GPNMB antibody, gpnmb.L antibody

Background: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein.GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines.GPNMB may be involved in growth delay and reduction of metastatic potential.Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 64 kDa

Gene ID: 10457

UniProt: Q14956