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SOCS1 antibody (Suppressor of Cytokine Signaling 1) (C-Term)

Details for Product anti-SOCS1 Antibody No. ABIN184575, Supplier: Log in to see
Antigen
  • CIS1
  • cis1
  • CISH1
  • cish1
  • Cish1
  • Cish7
  • jab
  • JAB
  • LOC100228306
  • Socs-1
  • socs-1
  • SOCS-1
  • SOCS1
  • socs1
  • socs1b
  • SSI-1
  • ssi-1
  • SSI1
  • ssi1
  • TIP3
  • tip3
  • zgc:91868
Alternatives
anti-Human SOCS1 antibody for ELISA
Epitope
C-Term
59
27
13
5
4
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Human
151
65
55
8
8
4
2
2
1
Host
Goat
136
17
10
Clonality
Polyclonal
Conjugate
This SOCS1 antibody is un-conjugated
7
7
6
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Methode Type
Peptide ELISA
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
140
54
33
29
11
10
8
8
4
4
2
1
Supplier
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Immunogen Peptide with sequence C-VLRDYLSSFPFQI, from the C Terminus of the protein sequence according to NP_003736.1.
Blocking Peptide Blocking peptide for this product available: ABIN370024
Cross-Reactivity Rat (Rattus), Dog (Canine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name SOCS1 (SOCS1 Antibody Abstract)
Background Synonyms: SOCS1, JAB, CIS1, SSI1, TIP3, CISH1, Cish1, SSI-1, SOCS-1, suppressor of cytokine signaling 1, JAK binding protein, Tec-interacting protein 3, STAT induced SH3 protein 1, cytokine-inducible SH2 protein 1
Gene ID 8651, 12703
NCBI Accession NP_003736
Research Area Chromatin and Nuclear Signaling, Signaling, Cytokines
Pathways JAK-STAT Signaling, Interferon-gamma Pathway, TLR Signaling
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: In transfected HEK293 transiently expressing human SOCS1 bands of approx. 30 kDa and 25 kDa are observed. These bands are not observed in the non-transfected HEK293. A similar pattern is observed in Mouse Spleen lysates. The calculated molecular size is 23.6 kDa according to Human NP_003736.1 and 23.7 kDa according to Mouse NP_034026.1. Recommended concentration: 1-3 µg/mL.
IHC: In paraffin embedded Human Kidney shows strong staining of the Brush Border in PCT. Recommended concentration: 2-3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (C-Term) (ABIN184575) ABIN184575 staining (2 µg/mL) of mouse spleen lysate (RIPA buffer, 35 µg total protei...
 image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (C-Term) (ABIN184575) HEK293 overexpressing SOCS1 and probed with ABIN184575 (mock transfection in lane B).
 image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (C-Term) (ABIN184575) ABIN184575 (2.5 µg/mL) staining of paraffin embedded Human Kidney. Steamed antigen re...
Background publications Starr, Willson, Viney, Murray, Rayner, Jenkins, Gonda, Alexander, Metcalf, Nicola, Hilton: "A family of cytokine-inducible inhibitors of signalling." in: Nature, Vol. 387, Issue 6636, pp. 917-21, 1997