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Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) antibody

Antigen

Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB)
Synonyms IP, SDH, PGL4, SDH1, SDH2, SDHIP, FLJ92337, 0710008N11Rik, MGC127046, Ip, MGC53699, MGC130803, fj46d06, MGC165456, wu:fj46d06
Clonality Polyclonal
Host
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA, Western Blotting (WB)
2 references available
Catalog no. ABIN185447
Quantity 100 ug
Price 374.27 $   Plus shipping costs $45.00
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anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) antibody

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name SDHB
Gene ID 6390
Immunogen C-ATYKEKKASV
Description All names and symbols: SDHB, IP, SDH, SDH1, SDHIP, succinate dehydrogenase complex, subunit B, iron sulfur (Ip), OTTHUMP00000044624, iron-sulfur subunit. Official Symbol: SDHB. RefSeq number(s): NP_002991.1. Gene ontology terms: electron transport, electron transporter activity, iron ion binding, membrane, mitochondrion, oxidoreductase activity, succinate dehydrogenase (ubiquinone) activity, tricarboxylic acid cycle
Specificity Human

Application Details
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Application Notes Peptide ELISA: antibody detection limit dilution 1:8,000. Western Blot: Approx 28kDa band observed in Human Liver lysates (calculated MW of 31.6kDa according to NP_002991.1). Recommended concentration: 0.03-0.1µg/ml.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Aliquot and store at -20°C. Minimize freezing and thawing.
Research Area Metabolism
Restrictions For Research Use only

Publications
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Morris, Maina, Morgan et al.: "Molecular genetic analysis of FIH-1, FH, and SDHB candidate tumour suppressor genes in renal cell carcinoma." in: Journal of clinical pathology, Vol. 57, Issue 7, pp. 706-11, 2004 (PubMed).

Selak, Armour, MacKenzie et al.: "Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase." in: Cancer cell, Vol. 7, Issue 1, pp. 77-85, 2005 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB)", type "Antibodies"
Hosts Rabbit (28), Goat (4)
Reactivities Human (29), Mouse (Murine) (23), Rat (Rattus) (22), Cow (Bovine) (19), Dog (Canine) (19), Pig (Porcine) (19), Horse (Equine) (18), Rabbit (1)
Applications Immunofluorescence (IF) (15), Western Blotting (WB) (15), ELISA (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (3), Center (1), Internal Region (1), N-Term (1)