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Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) antibody
| Antigen | Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) |
| Synonyms | IP, SDH, PGL4, SDH1, SDH2, SDHIP, FLJ92337, 0710008N11Rik, MGC127046, Ip, MGC53699, MGC130803, fj46d06, MGC165456, wu:fj46d06 |
| Clonality | Polyclonal |
| Host |
Alternatives Goat |
| Reactivity |
Alternatives Human |
| Application |
Alternatives ELISA, Western Blotting (WB)
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2 references available |
| Catalog no. | ABIN185447 |
| Quantity | 100 ug |
| Price | 501.80 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 Business Days |
Additional Information
| Alternative name | SDHB |
| Gene ID | 6390 |
| Immunogen | C-ATYKEKKASV |
| Format | Affinity-purified |
| Description | All names and symbols: SDHB, IP, SDH, SDH1, SDHIP, succinate dehydrogenase complex, subunit B, iron sulfur (Ip), OTTHUMP00000044624, iron-sulfur subunit. Official Symbol: SDHB. RefSeq number(s): NP_002991.1. Gene ontology terms: electron transport, electron transporter activity, iron ion binding, membrane, mitochondrion, oxidoreductase activity, succinate dehydrogenase (ubiquinone) activity, tricarboxylic acid cycle |
| Specificity | Human |
Application Details
| Application Notes | Peptide ELISA: antibody detection limit dilution 1:8,000. Western Blot: Approx 28kDa band observed in Human Liver lysates (calculated MW of 31.6kDa according to NP_002991.1). Recommended concentration: 0.03-0.1µg/ml. |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| Research Area | Metabolism |
| Restrictions | For Research Use only |
Images
| ABIN185447 (0.03µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
Publications
| Publications |
Morris, Maina, Morgan et al.: "Molecular genetic analysis of FIH-1, FH, and SDHB candidate tumour suppressor genes in renal cell carcinoma." in: Journal of clinical pathology, Vol. 57, Issue 7, pp. 706-11, 2004 (PubMed).
Selak, Armour, MacKenzie et al.: "Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase." in: Cancer cell, Vol. 7, Issue 1, pp. 77-85, 2005 (PubMed). |
Alternatives
Alternatives for antigen "Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB)", type "Antibodies"
| Hosts | Rabbit (23), Goat (2) |
| Reactivities | Human (23), Mouse (Murine) (19), Rat (Rattus) (19), Dog (Canine) (16), Pig (Porcine) (16), Rabbit (16), Cow (Bovine) (15), Horse (Equine) (15) |
| Applications | Flow Cytometry (FACS) (18), Immunofluorescence (IF) (18), Western Blotting (WB) (7), ELISA (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), ELISA (Detection) (1), Enzyme Immunoassay (EIA) (1), Immunoelectron Microscopy (IEM) (1) |
| Conjugates | Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |




Alternatives