NR2E1 antibody (AA 75-102)
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- Target See all NR2E1 Antibodies
- NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))
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Binding Specificity
- AA 75-102
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR2E1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Predicted Reactivity
- C, M, X
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This NR2E1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-102 amino acids from the Central region of human NR2E1.
- Clone
- RB41747
- Isotype
- Ig Fraction
- Top Product
- Discover our top product NR2E1 Primary Antibody
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- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation." in: Genes & development, Vol. 24, Issue 7, pp. 683-95, (2010) (PubMed).
: "Transcriptional activation of NAD+-dependent protein deacetylase SIRT1 by nuclear receptor TLX." in: Biochemical and biophysical research communications, Vol. 386, Issue 4, pp. 671-5, (2009) (PubMed).
: "A common variant in DRD3 receptor is associated with autism spectrum disorder." in: Biological psychiatry, Vol. 65, Issue 7, pp. 625-30, (2009) (PubMed).
: "Transrepressive function of TLX requires the histone demethylase LSD1." in: Molecular and cellular biology, Vol. 28, Issue 12, pp. 3995-4003, (2008) (PubMed).
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The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation." in: Genes & development, Vol. 24, Issue 7, pp. 683-95, (2010) (PubMed).
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- Target
- NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))
- Alternative Name
- NR2E1 (NR2E1 Products)
- Synonyms
- NR2E1 antibody, TLL antibody, TLX antibody, XTLL antibody, Mtl1 antibody, Mtll antibody, Tlx antibody, fierce antibody, frc antibody, tailless antibody, fc30e03 antibody, fc39f12 antibody, wu:fc30e03 antibody, wu:fc39f12 antibody, zgc:100991 antibody, Xtll antibody, nr2e1-A antibody, tlx antibody, nuclear receptor subfamily 2 group E member 1 antibody, nuclear receptor subfamily 2, group E, member 1 antibody, nuclear receptor subfamily 2 group E member 1 S homeolog antibody, NR2E1 antibody, Nr2e1 antibody, nr2e1 antibody, nr2e1.S antibody
- Background
- Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development (By similarity).
- Molecular Weight
- 42589
- NCBI Accession
- NP_003260
- UniProt
- Q9Y466
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance
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