CARD9
Reactivity: Human
WB, IF, EIA
Host: Rabbit
Polyclonal
unconjugated
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice
Avoid freezing and thawing repeatly.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Target
CARD9
(Caspase Recruitment Domain Family, Member 9 (CARD9))
Gm782 antibody, card9 antibody, CANDF2 antibody, hCARD9 antibody, caspase recruitment domain family, member 9 antibody, caspase recruitment domain family member 9 antibody, Card9 antibody, CARD9 antibody, card9 antibody
Background
Apoptosis is related to many diseases and development.Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules.CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC.A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10.CARD9 associates with BCL-10 and forms a complex within cells.CARD9 induces apoptosis and activates NF-kappaB.CARD9 is an upstream activator of BCL-10 and NF-kappaB signaling.