NSRP1 antibody (C-Term)

Catalog No. ABIN1887131

Product Details anti-NSRP1 Antibody

Target: NSRP1 (Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSRP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: At least three isoforms are known to exist, this antibody will detect all three.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human CCDC55.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for NSRP1

Target: NSRP1 (Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))

Alternative Name: CCDC55 (NSRP1 Products)

Synonyms: 8030451K07 antibody, AI851076 antibody, AL022898 antibody, NSpr70 antibody, NSrp70 antibody, Nsrp1 antibody, CCDC55 antibody, HSPC095 antibody, Ccdc55 antibody, RGD1309863 antibody, fc14d05 antibody, wu:fc14d05 antibody, zgc:152777 antibody, nuclear speckle regulatory protein 1 antibody, nuclear speckle splicing regulatory protein 1 antibody, Nsrp1 antibody, NSRP1 antibody, nsrp1 antibody

Background: CCDC55, also known as Nuclear speckle-related protein 70 (NSrp70), was initially identified by the NIH Mammalian Gene Collection.Nuclear speckles are known to be the storage sites of mRNA splicing regulators.CCDC55 has been suggested to modulate alternative pre-mRNA splicing in vivo.It co-localizes and physically interacts with the SR proteins SC35 and ASF/SF2, essential splicing factors which are required for constitutive splicing and can regulate alternative mRNA splicing.Loss of CCDC55 in mice leads to early embryonic lethality highlights the importance of the functional role of CCDC55.
Synonyms: Coiled-coil domain-containing protein 55, HSPC095, NSrp70

NCBI Accession: NP_115517