SARM1 antibody (C-Term)

Catalog No. ABIN1887395

Product Details anti-SARM1 Antibody

Target: SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Ion exchange chromatography purified

Immunogen: Peptide corresponding to amino acids near the C-terminus of human SARM.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for SARM1

Target: SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

Alternative Name: SARM (SARM1 Products)

Synonyms: A830091I15Rik antibody, C78606 antibody, MyD885 antibody, Sarm antibody, MyD88-5 antibody, SAMD2 antibody, SARM antibody, sterile alpha and TIR motif containing 1 antibody, sterile alpha and HEAT/Armadillo motif containing 1 antibody, SARM1 antibody, Sarm1 antibody, sarm1 antibody

Background: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF-kappaB, and ultimately the expression of proteins involved in host defense.While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interluekin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.

NCBI Accession: NP_055892

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades