SLC39A6 antibody (Center)

Catalog No. ABIN1887631

Product Details anti-SLC39A6 Antibody

Target: SLC39A6 (Solute Carrier Family 39 (Zinc Transporter), Member 6 (SLC39A6))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC39A6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the center of human ZIP6.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for SLC39A6

Target: SLC39A6 (Solute Carrier Family 39 (Zinc Transporter), Member 6 (SLC39A6))

Alternative Name: ZIP6 (SLC39A6 Products)

Synonyms: liv1 antibody, wu:fc25a09 antibody, ZIP6 antibody, Ermelin antibody, LIV-1 antibody, solute carrier family 39 (zinc transporter), member 6 antibody, solute carrier family 39 member 6 antibody, solute carrier family 39 (metal ion transporter), member 6 antibody, slc39a6 antibody, SLC39A6 antibody, Slc39a6 antibody

Background: The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters.Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation.ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer.Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line, down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.
Synonyms: Solute carrier family 39 member A6, Slc39A6, LIV-1

NCBI Accession: NP_001092876

Pathways: Transition Metal Ion Homeostasis