ATP11A antibody (N-Term)

Catalog No. ABIN1888107

Product Details anti-ATP11A Antibody

Target: ATP11A (ATPase, Class VI, Type 11A (ATP11A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP11A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the amino terminus of human ATP11A.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for ATP11A

Target: ATP11A (ATPase, Class VI, Type 11A (ATP11A))

Alternative Name: ATP11A (ATP11A Products)

Synonyms: ATPIH antibody, ATPIS antibody, 4930558F19Rik antibody, AU040868 antibody, Atpc1h antibody, Ih antibody, Ua20 antibody, si:dkey-251i8.1 antibody, ATPase phospholipid transporting 11A antibody, ATPase, class VI, type 11A antibody, ATP11A antibody, Atp11a antibody, atp11a antibody

Background: ATP11A is a widely expressed integral membrane ATPase.ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes.While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs).Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug.Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.
Synonyms: ATPase class VI type 11A, ATPIH, ATPIS

NCBI Accession: NP_115565