TLR4 antibody (N-Term)
-
- Target See all TLR4 Antibodies
- TLR4 (Toll-Like Receptor 4 (TLR4))
-
Binding Specificity
- N-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TLR4 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Purification
- Ion exchange chromatography purified
- Immunogen
- Peptide corresponding to 15 amino acids near the amino-terminus of human TLR4.
- Top Product
- Discover our top product TLR4 Primary Antibody
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Handling Advice
- Avoid freezing and thawing repeatly.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
-
- Target
- TLR4 (Toll-Like Receptor 4 (TLR4))
- Alternative Name
- TLR4 (TLR4 Products)
- Synonyms
- ARMD10 antibody, CD284 antibody, TLR-4 antibody, TOLL antibody, Lps antibody, Ly87 antibody, Ran/M1 antibody, Rasl2-8 antibody, toll like receptor 4 antibody, toll-like receptor 4 antibody, TLR4 antibody, Tlr4 antibody
- Background
-
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kappaB.Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide.Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.
- NCBI Accession
- NP_612564
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
-