RBP4 antibody
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- Target See all RBP4 Antibodies
- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This RBP4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- Specific for native and denatured forms
- Cross-Reactivity
- Human, Mouse
- Purification
- Protein G purified
- Immunogen
- Recombinant Human Retinol-binding protein 4 protein
- Clone
- 6A1C2
- Isotype
- IgG1, IgG1 kappa
- Top Product
- Discover our top product RBP4 Primary Antibody
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- Application Notes
- Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
- Alternative Name
- RBP4 (RBP4 Products)
- Synonyms
- RDCCAS antibody, RBP antibody, RNBP antibody, rbp4 antibody, MGC54038 antibody, srbp antibody, PRBP antibody, RBPA antibody, Rbp-4 antibody, fb23c12 antibody, rbp antibody, wu:fb23c12 antibody, wu:fb58d04 antibody, wu:fb72b04 antibody, zgc:86911 antibody, retinol binding protein 4 antibody, renin binding protein antibody, retinol binding protein 4 S homeolog antibody, retinol binding protein 4 A, plasma antibody, retinol binding protein 4, plasma antibody, retinol binding protein 4 L homeolog antibody, RBP4 antibody, RENBP antibody, rbp4.S antibody, rbp4 antibody, Rbp4 antibody, RBP4A antibody, rbp4.L antibody
- Background
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Background: Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.
Aliases: Plasma retinol-binding protein, PRBP, RBP, RBP4, PRO2222
- UniProt
- P02753
- Pathways
- Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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