CTLA4 antibody

Catalog No. ABIN1994767

Product Details anti-CTLA4 Antibody

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTLA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Affinity purification

Immunogen: A synthetic peptide of Human CTLA4

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2000, IHC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Store at -20 °C or -80 °C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Alternative Name: CTLA4 (CTLA4 Products)

Synonyms: CTLA-4 antibody, CTLA4 antibody, CD152 antibody, Cd152 antibody, Ctla-4 antibody, Ly-56 antibody, CD antibody, CELIAC3 antibody, GRD4 antibody, GSE antibody, IDDM12 antibody, sCTLA4 antibody, cytotoxic T-lymphocyte associated protein 4 antibody, cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA4 antibody, Ctla4 antibody

Background:

Background: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]

Aliases: ALPS5 antibody, CD 152 antibody, CD antibody, CD152 antibody, CD152 antigen antibody, CD152 isoform antibody, Celiac disease 3 antibody, CELIAC3 antibody, CTLA 4 antibody, CTLA-4 antibody, CTLA4 antibody, CTLA4_HUMAN antibody, Cytotoxic T cell associated 4 antibody, Cytotoxic T lymphocyte antigen 4 antibody, Cytotoxic T lymphocyte associated 4 antibody, Cytotoxic T lymphocyte associated 4, soluble isoform, included antibody, Cytotoxic T lymphocyte associated antigen 4 antibody, Cytotoxic T lymphocyte associated antigen 4 short spliced form antibody, Cytotoxic T lymphocyte associated protein 4 antibody, Cytotoxic T lymphocyte associated serine esterase 4 antibody, Cytotoxic T lymphocyte protein 4 antibody, Cytotoxic T-lymphocyte protein 4 antibody, Cytotoxic T-lymphocyte-associated antigen 4 antibody, GRD4 antibody, GSE antibody, ICOS antibody, IDDM12 antibody, insulin-dependent diabetes mellitus 12 antibody, Ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 antibody, OTTHUMP00000216623 antibody

Pathways: Cancer Immune Checkpoints