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TLR4 antibody (Biotin)

TLR4 Reactivity: Human, Dog, Pig, Guinea Pig, Rhesus Monkey WB, FACS, IP Host: Mouse Monoclonal Biotin
Catalog No. ABIN206336
  • Target See all TLR4 Antibodies
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Reactivity
    • 173
    • 90
    • 75
    • 37
    • 22
    • 19
    • 19
    • 18
    • 4
    • 2
    • 1
    • 1
    Human, Dog, Pig, Guinea Pig, Rhesus Monkey
    Host
    • 129
    • 69
    • 5
    • 4
    Mouse
    Clonality
    • 133
    • 74
    Monoclonal
    Conjugate
    • 92
    • 21
    • 20
    • 14
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR4 antibody is conjugated to Biotin
    Application
    • 150
    • 124
    • 54
    • 49
    • 35
    • 27
    • 27
    • 26
    • 26
    • 23
    • 13
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
    Specificity
    Recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. Has been demonstrated to block activation of monocytes with LPS. XXX recommend the use of MCA2061EL for this purpose.
    Purification
    Protein G purified
    Immunogen
    Ba/F3 cell line expressing TLR4 (CD284).
    Isotype
    IgG2a
    Top Product
    Discover our top product TLR4 Primary Antibody
  • Application Notes
    Approved: Flo, IP, WB

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or cells or 100 μL whole blood. Method sheets are available on request.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS, 0.09 % sodium azide, 1 % BSA.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Alternative Name
    TLR4 (TLR4 Products)
    Synonyms
    ARMD10 antibody, CD284 antibody, TLR-4 antibody, TOLL antibody, Lps antibody, Ly87 antibody, Ran/M1 antibody, Rasl2-8 antibody, toll like receptor 4 antibody, toll-like receptor 4 antibody, TLR4 antibody, Tlr4 antibody
    Background
    Name/Gene ID: TLR4
    Family: Toll-like Receptor

    Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll
    Gene ID
    7099
    UniProt
    O00206
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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