CD8B antibody

Catalog No. ABIN206835

Product Details anti-CD8B Antibody

Target: CD8B (CD8b Molecule (CD8B))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD8B antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: Recognizes the beta chain of the rat CD8 cell surface antigen, expressed on thymocytes and peripheral cytotoxic/suppressor cells. CD8b is not expressed by NK cells or by intestinal intraepithelial T cells. Is reported to block proliferative and cytotoxic responses of CD8 +ve effector cells in vitro.

Purification: Protein G purified

Immunogen: Rat/mouse T cell hybrids expressing CD8.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:100 - 1:200), IP

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CD8B

Target: CD8B (CD8b Molecule (CD8B))

Alternative Name: CD8B / CD8 beta (CD8B Products)

Synonyms: Cd8b antibody, Ly-3 antibody, Ly-C antibody, Lyt-3 antibody, CD8B1 antibody, LEU2 antibody, LY3 antibody, LYT3 antibody, P37 antibody, Cd8b1 antibody, CD8b molecule antibody, CD8 antigen, beta chain 1 antibody, Cd8b antibody, CD8B antibody, Cd8b1 antibody

Background: Name/Gene ID: CD8B

Synonyms: CD8B, CD8b antigen, CD8b molecule, CD8B1, p37, LY3, LYT3, Leu2

Gene ID: 926

UniProt: P10966

Pathways: TCR Signaling