XRCC5 antibody

Catalog No. ABIN207129

The Mouse Monoclonal anti-XRCC5 antibody (Clone MEM-54) (ABIN207129) specifically detects XRCC5 in IP and ICC. The antibody is reactive with Human samples.

Quick Overview for XRCC5 antibody (ABIN207129)

Target: XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This XRCC5 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: MEM-54

Product Details anti-XRCC5 Antibody

Specificity: Reacts with Ku80, a 80 kD subunit of Ku autoantigen (heterodimer of 72 and 87 kD polypeptides). Ku autoantigen is involved in DNA repair and in V(D)J recombination through its ability to bind DNA double-strand breaks.

Purification: Protein A purified

Immunogen: Human whole T-lymphocytes.

Isotype: IgG2a

Application Details

Application Notes: Approved: ICC (2 μg/mL), IP

Usage: Immunocytochemistry: Recommended dilution -. Purified Antibody: 2 μg/mL. Staining technique: PFA-fixation.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide, approx,  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for XRCC5

Target: XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))

Alternative Name: XRCC5 / Ku80

Background: Name/Gene ID: XRCC5

Synonyms: XRCC5, 86 kDa subunit of Ku antigen, CTC85, CTCBF, DNA repair protein XRCC5, G22P2, KARP-1, Ku autoantigen, 80  kDa, NFIV, KARP1, Ku86, KUB2, TLAA, Nuclear factor IV, KU80, Thyroid-lupus autoantigen

Gene ID: 7520

UniProt: P13010

Pathways: DNA Damage Repair