XRCC5 antibody (AA 1-732)

Catalog No. ABIN563391

Cited in 3+ publications. The Mouse Monoclonal anti-XRCC5 antibody (Clone 3D8) (ABIN563391) specifically detects XRCC5 in WB, ELISA, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for XRCC5 antibody (AA 1-732) (ABIN563391)

Target: XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This XRCC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3D8

Product Details anti-XRCC5 Antibody

Binding Specificity: AA 1-732

Purpose: Mouse monoclonal antibody raised against a full length recombinant XRCC5.

Sequence: MVRSGNKAAV VLCMDVGFTM SNSIPGIESP FEQAKKVITM FVQRQVFAEN KDEIALVLFG TDGTDNPLSG GDQYQNITVH RHLMLPDFDL LEDIESKIQP GSQQADSLDA LIVSMDVIQH ETIGKKFEKR HIEIFTDLSS RFSKSQLDII IHSLKKCDIS LQFFLPFSLG KEDGSGDRGD GPFRLGGHGP SFPLKGITEQ QKEGLEIVKM VMISLEGEDG LDEIYSFSES LRKLCVFKKI ERHSIHWPCR LTIGSNLSIR IAAYKSILQE RVKKTWTVVD AKTLKKEDIQ KETVYCLNDD DETEVLKEDI IQGFRYGSDI VPFSKVDEEQ MKYKSEGKCF SVLGFCKSSQ VQRRFFMGNQ VLKVFAARDD EAAAVALSSL IHALDDLDMV AIVRYAYDKR ANPQVGVAFP HIKHNYECLV YVQLPFMEDL RQYMFSSLKN SKKYAPTEAQ LNAVDALIDS MSLAKKDEKT DTLEDLFPTT KIPNPRFQRL FQCLLHRALH PREPLPPIQQ HIWNMLNPPA EVTTKSQIPL SKIKTLFPLI EAKKKDQVTA QEIFQDNHED GPTAKKLKTE QGGAHFSVSS LAEGSVTSVG SVNPAENFRV LVKQKKASFE EASNQLINHI EQFLDTNETP YFMKSIDCIR AFREEAIKFS EEQRFNNFLK ALQEKVEIKQ LNHFWEIVVQ DGIALITKEE ASGSSVTAEE AKKFLAPKDK PSGDTAAVFE EGGDVDDLLD MI

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: XRCC5 (AAH19027.1, 1 a.a. ~ 732 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-XRCC5 antibody (ABIN563391)

Hori, Someya, Matsumoto, Nakata, Kitagawa, Hasegawa, Tsuchiya, Fukushima, Gocho, Sato, Ohnuma, Kato, Sugita, Hasegawa, Sakata: "Influence of XRCC4 expression in esophageal cancer cells on the response to radiotherapy." in: Medical molecular morphology, Vol. 50, Issue 1, pp. 25-33, (2016) (PubMed).

Hasegawa, Someya, Hori, Matsumoto, Nakata, Nojima, Kitagawa, Tsuchiya, Masumori, Hasegawa, Sakata: "Expression of Ku70 predicts results of radiotherapy in prostate cancer." in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], Vol. 193, Issue 1, pp. 29-37, (2016) (PubMed).

Nomura, Sogawa, Noda, Seimiya, Matsushita, Miura, Tomonaga, Yoshitomi, Imazeki, Takizawa, Mogushi, Miyazaki, Yokosuka: "Serum anti-Ku86 is a potential biomarker for early detection of hepatitis C virus-related hepatocellular carcinoma." in: Biochemical and biophysical research communications, Vol. 421, Issue 4, pp. 837-43, (2012) (PubMed).

Target Details for XRCC5

Target: XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))

Alternative Name: XRCC5

Background: Full Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Synonyms: FLJ39089,KARP-1,KARP1,KU80,KUB2,Ku86,NFIV

Gene ID: 7520

Pathways: DNA Damage Repair