MTOR antibody (pSer2448)
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- Target See all MTOR (mTOR) Antibodies
- MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
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Binding Specificity
- pSer2448
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MTOR antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- Detects endogenous levels of human mTOR only when phosphorylated at Ser2448. MW: 289kD. Species cross-reactivity: human. Species sequence homology: mouse -100 % .
- Purification
- Protein A purified
- Immunogen
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Synthetic phosphopeptide corresponding to residues surrounding Ser2448 of human mTOR (KLH coupled).
Type of Immunogen: Synthetic phospho-peptide - Isotype
- IgG
- Top Product
- Discover our top product mTOR Primary Antibody
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- Application Notes
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Approved: ELISA, IHC, IHC-Fr, IHC-P (1:50)
Usage: Suitable for use in ELISA and Immunohistochemistry. Immunohistochemistry (Paraffin and Frozen): 1:50. Citrate/TBST. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol, 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
- Alternative Name
- MTOR (mTOR Products)
- Synonyms
- FRAP1 antibody, FRAP antibody, FRAP2 antibody, RAFT1 antibody, RAPT1 antibody, 2610315D21Rik antibody, AI327068 antibody, Frap1 antibody, flat antibody, frap1 antibody, tor antibody, wu:fc22h08 antibody, mechanistic target of rapamycin kinase antibody, mechanistic target of rapamycin antibody, mechanistic target of rapamycin (serine/threonine kinase) antibody, MTOR antibody, Mtor antibody, mtor antibody
- Background
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Name/Gene ID: MTOR
Subfamily: PI3/PI4
Family: Protein Kinase
Synonyms: MTOR, FRAP1, FRAP2, FRAP, Mammalian target of rapamycin, RAFT1, Rapamycin and FKBP12 target 1, RAPT1, Rapamycin target protein 1 - Gene ID
- 2475
- UniProt
- P42345
- Pathways
- PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect
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