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Presenilin 1 antibody (Val293)

PSEN1 Reactivity: Human WB, ELISA, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6735742
  • Target See all Presenilin 1 (PSEN1) Antibodies
    Presenilin 1 (PSEN1)
    Binding Specificity
    • 31
    • 15
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Val293
    Reactivity
    • 105
    • 90
    • 59
    • 9
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 93
    • 36
    • 2
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 128
    • 7
    Polyclonal
    Conjugate
    • 45
    • 11
    • 10
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Presenilin 1 antibody is un-conjugated
    Application
    • 104
    • 52
    • 52
    • 50
    • 39
    • 18
    • 15
    • 13
    • 9
    • 7
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Specificity
    Detects endogenous levels of the carboxy-terminal fragment of presenilin 1 (~22kD). The antibody detects the full length protein (55kD) to a lesser extent. Species cross-reactivity: Human, rat and monkey. Species sequence homology: mouse 100 % .
    Purification
    Immunoaffinity purified
    Immunogen
    Synthetic peptide (KLH coupled) corresponding to residues around valine 293 of human presenilin 1.

    Type of Immunogen: Synthetic peptide
    Isotype
    IgG
    Top Product
    Discover our top product PSEN1 Primary Antibody
  • Application Notes
    Approved: ELISA, IP (1:100), WB (1:500)

    Usage: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western Blot: 1:500. Immunoprecipitation: 1:100.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target
    Presenilin 1 (PSEN1)
    Alternative Name
    PSEN1 / Presenilin 1 (PSEN1 Products)
    Synonyms
    pre1 antibody, psen antibody, zfPS1 antibody, zf-PS1 antibody, ad3 antibody, fad antibody, ps1 antibody, s182 antibody, X-PS-beta antibody, X-PS-alpha antibody, AD3 antibody, FAD antibody, PS-1 antibody, PS1 antibody, S182 antibody, Ad3h antibody, presenilin 1 antibody, presenilin 1 L homeolog antibody, psen1 antibody, PSEN1 antibody, Psen1 antibody, psen1.L antibody
    Background
    Name/Gene ID: PSEN1
    Subfamily: Aspartic A22A
    Family: protease

    Synonyms: PSEN1, AD3, Alzheimer disease 3, FAD, Protein S182, PS1, S182, PS-1, PSNL1, Presenilin 1, Presenilin-1
    Gene ID
    5663
    UniProt
    P49768
    Pathways
    Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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