ALKBH2 antibody

Catalog No. ABIN2422380

Product Details anti-ALKBH2 Antibody

Target: ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALKBH2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity purification

Immunogen: Recombinant protein of human ALKBH2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ALKBH2

Target: ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))

Alternative Name: ALKBH2 (ALKBH2 Products)

Synonyms: si:dkey-65b12.2 antibody, ABH2 antibody, 9530023G02 antibody, AU016977 antibody, Abh2 antibody, mABH2 antibody, RGD1306377 antibody, alkB homolog 2, alpha-ketoglutarate dependent dioxygenase antibody, alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase antibody, ALKBH2 antibody, alkbh2 antibody, Alkbh2 antibody

Background: The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.

Molecular Weight: Calculated MW: 29 kDa

Pathways: DNA Damage Repair