KIRREL antibody
-
- Target See all KIRREL (NEPH1) Antibodies
- KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))
-
Reactivity
- Human, Rat, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This KIRREL antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KIRREL.
- Top Product
- Discover our top product NEPH1 Primary Antibody
-
-
- Application Notes
- KIRREL antibody can be used for detection of KIRREL by ELISA at 1:312500. KIRREL antibody can be used for detection of KIRREL by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store KIRREL antibody at -20 °C.
-
- Target
- KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))
- Alternative Name
- KIRREL (NEPH1 Products)
- Synonyms
- NEPH1 antibody, 6720469N11Rik antibody, Kirrel1 antibody, Neph1 antibody, nephrin related antibody, kirre like nephrin family adhesion molecule 1 antibody, kin of IRRE like (Drosophila) antibody, Smp_104390 antibody, Smp_140170 antibody, KIRREL1 antibody, Kirrel antibody, Kirrel1 antibody
- Background
- KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2, MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).
- Molecular Weight
- 66 kDa
- Gene ID
- 55243
- NCBI Accession
- NP_060710
- UniProt
- Q5W0F9
- Pathways
- Regulation of Actin Filament Polymerization
-