GPX3 antibody

Catalog No. ABIN2462422

Product Details anti-GPX3 Antibody

Target: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GPX3.

Application Details

Application Notes: GPX3 antibody can be used for detection of GPX3 by ELISA at 1:312500. GPX3 antibody can be used for detection of GPX3 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GPX3 antibody at -20 °C.

Target Details for GPX3

Target: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Alternative Name: GPX3 (GPX3 Products)

Synonyms: GPX3 antibody, DKFZp469D1932 antibody, AA960521 antibody, EGPx antibody, GPx antibody, GSHPx-3 antibody, GSHPx-P antibody, GPx-3 antibody, GPx-P antibody, Gpxp antibody, glutathione peroxidase 3 antibody, gpx3 antibody, GPX3 antibody, Gpx3 antibody

Background: GPX3 belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme. GPX3 expression appears to be tissue-specific.

Molecular Weight: 25 kDa

Gene ID: 2878

NCBI Accession: NP_002075

UniProt: P22352

Pathways: Thyroid Hormone Synthesis