DECR2 antibody

Catalog No. ABIN2462714

Product Details anti-DECR2 Antibody

Target: DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DECR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DECR2.

Application Details

Application Notes: DECR2 antibody can be used for detection of DECR2 by ELISA at 1:312500. DECR2 antibody can be used for detection of DECR2 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DECR2 antibody at -20 °C.

Target Details for DECR2

Target: DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))

Alternative Name: DECR2 (DECR2 Products)

Synonyms: PDCR antibody, SDR17C1 antibody, zC153C20.5 antibody, zgc:85626 antibody, Dcrakl antibody, putativeperoxisomal24-dienoyl-CoAreductase antibody, 2,4-dienoyl-CoA reductase 2 antibody, 2,4-dienoyl CoA reductase 2, peroxisomal antibody, 2,4-dienoyl-CoA reductase 2 L homeolog antibody, 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal antibody, DECR2 antibody, decr2 antibody, decr2.L antibody, Decr2 antibody

Background: DECR2 is auxiliary enzyme of beta-oxidation. It participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. It catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA and has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.

Molecular Weight: 32 kDa

Gene ID: 26063

NCBI Accession: NP_065715

UniProt: Q9NUI1