TTC5 antibody

Catalog No. ABIN2463249

Product Details anti-TTC5 Antibody

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TTC5.

Application Details

Application Notes: TTC5 antibody can be used for detection of TTC5 by ELISA at 1:312500. TTC5 antibody can be used for detection of TTC5 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TTC5 antibody at -20 °C.

Target Details for TTC5

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Alternative Name: TTC5 (TTC5 Products)

Synonyms: TTC5 antibody, ttc5 antibody, wu:fi33h05 antibody, wu:fy81e07 antibody, zgc:112059 antibody, Strap antibody, 5930437N14 antibody, AW743060 antibody, tetratricopeptide repeat domain 5 L homeolog antibody, tetratricopeptide repeat domain 5 antibody, ttc5.L antibody, TTC5 antibody, ttc5 antibody, Ttc5 antibody

Background: TTC5 is an adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. It is required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. It prevents p53/TP53 degradation by MDM2.

Molecular Weight: 49 kDa

Gene ID: 91875

NCBI Accession: NP_612385

UniProt: Q8N0Z6

Pathways: Chromatin Binding