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TTC5 antibody

TTC5 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2463249
  • Target See all TTC5 Antibodies
    TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))
    Reactivity
    • 16
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 16
    • 1
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 13
    • 2
    • 1
    • 1
    This TTC5 antibody is un-conjugated
    Application
    • 12
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TTC5.
    Top Product
    Discover our top product TTC5 Primary Antibody
  • Application Notes
    TTC5 antibody can be used for detection of TTC5 by ELISA at 1:312500. TTC5 antibody can be used for detection of TTC5 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store TTC5 antibody at -20 °C.
  • Target
    TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))
    Alternative Name
    TTC5 (TTC5 Products)
    Synonyms
    TTC5 antibody, ttc5 antibody, wu:fi33h05 antibody, wu:fy81e07 antibody, zgc:112059 antibody, Strap antibody, 5930437N14 antibody, AW743060 antibody, tetratricopeptide repeat domain 5 L homeolog antibody, tetratricopeptide repeat domain 5 antibody, ttc5.L antibody, TTC5 antibody, ttc5 antibody, Ttc5 antibody
    Background
    TTC5 is an adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. It is required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. It prevents p53/TP53 degradation by MDM2.
    Molecular Weight
    49 kDa
    Gene ID
    91875
    NCBI Accession
    NP_612385
    UniProt
    Q8N0Z6
    Pathways
    Chromatin Binding
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