CTLA4 antibody
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- Target See all CTLA4 Antibodies
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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Reactivity
- Mouse
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Host
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Hamster
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Clonality
- Monoclonal
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Conjugate
- This CTLA4 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152.
- Purification
- The monoclonal antibody was purified utilizing affinity chromatography.
- Clone
- UC10-4F10-11
- Isotype
- IgG
- Top Product
- Discover our top product CTLA4 Primary Antibody
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anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibody (PE)
CTLA4 Reactivity: Human FACS Host: Mouse Monoclonal BNI3 PE
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-135) antibodyCTLA4 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 2F1 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibodyCTLA4 Reactivity: Human FACS, IP, ICC, IHC (fro) Host: Mouse Monoclonal BNI3 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibodyCTLA4 Reactivity: Human FACS, IP, ICC, IHC (fro) Host: Mouse Monoclonal BNI3 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-162) antibodyCTLA4 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 9D2E9 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) antibodyCTLA4 Reactivity: Human FACS, WB, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 8B3F8 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 41-90) antibodyCTLA4 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 52-211) antibodyCTLA4 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 75-170) antibodyCTLA4 Reactivity: Human, Mouse, Rat FACS, WB, ELISA, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 50-78) antibodyCTLA4 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB23352 unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- Storage
- 4 °C
- Storage Comment
- The product should be stored undiluted at 4°C. Do not freeze.
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- Target
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
- Alternative Name
- CD152 (CTLA4 Products)
- Synonyms
- CTLA-4 antibody, CTLA4 antibody, CD152 antibody, Cd152 antibody, Ctla-4 antibody, Ly-56 antibody, CD antibody, CELIAC3 antibody, GRD4 antibody, GSE antibody, IDDM12 antibody, sCTLA4 antibody, cytotoxic T-lymphocyte associated protein 4 antibody, cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA4 antibody, Ctla4 antibody
- Background
- The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
- Gene ID
- 12477
- UniProt
- P09793
- Pathways
- Cancer Immune Checkpoints
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