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Integrin Alpha2b antibody

CD41 Reactivity: Mouse FACS, Func Host: Rat Monoclonal MWReg30 unconjugated

Catalog No. ABIN2567694

Datasheet as PDF

Target See all Integrin Alpha2b (CD41) Antibodies

Integrin Alpha2b (CD41)
Reactivity
106

29

21

5

5

4

3

2

2

2

1

1

1

1

1
Mouse
Host
67

41

20
Rat
Compatible Secondaries
Clonality
83

39

1
Monoclonal
Conjugate
53

14

12

11

4

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Integrin Alpha2b antibody is un-conjugated
Application
94

41

26

25

19

18

13

13

10

9

8

5

2

1

1

1

1

1
Flow Cytometry (FACS), Functional Studies (Func)

Specificity

The MWReg30 monoclonal antibody specifically reacts with mouse CD41, a transmembrane glycoprotein also known as integrin alpha 2b GPIIb.

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Clone

MWReg30

Isotype

IgG1 kappa

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anti-Integrin Alpha2b (CD41) (AA 351-450) antibody
CD41 Reactivity: Human, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) (Internal Region) antibody
CD41 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p), Func Host: Rat Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p) Host: Rat Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP2 unconjugated

anti-Integrin Alpha2b (CD41) antibody (Biotin)
CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 Biotin

anti-Integrin Alpha2b (CD41) antibody (FITC)
CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 FITC

anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibody
CD41 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) (AA 639-887) antibody
CD41 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Storage

4 °C

Storage Comment

The product should be stored undiluted at 4°C. Do not freeze.
Target

Integrin Alpha2b (CD41)

Alternative Name

CD41 (CD41 Products)

Synonyms

AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody

Background

The MWReg30 monoclonal antibody specifically reacts with mouse CD41, a transmembrane glycoprotein also known as integrin alpha 2b GPIIb. It is expressed on hematopoietic progenitors, megakaryocytes, and platelets. It forms a receptor with CD61 (integrin beta 3) that binds adhesion molecules such as fibrinogen, fibronectin, von Willebrand factor, and thrombin. Defects or absence of CD41 has been found to lead to coagulation disorders. The expression profile of CD150+,CD48-, and CD41- can be used to identify hematopoietic stem cells.

Gene ID

16399

UniProt

Q9QUM0

Pathways

Integrin Complex