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Integrin Alpha2b antibody (FITC)

CD41 Reactivity: Mouse FACS Host: Rat Monoclonal MWReg30 FITC
Catalog No. ABIN2567697
  • Target See all Integrin Alpha2b (CD41) Antibodies
    Integrin Alpha2b (CD41)
    Reactivity
    • 106
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    Mouse
    Host
    • 67
    • 41
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    Rat
    Clonality
    • 83
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    Monoclonal
    Conjugate
    • 53
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    This Integrin Alpha2b antibody is conjugated to FITC
    Application
    • 94
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    Flow Cytometry (FACS)
    Specificity
    The MWReg30 monoclonal antibody specifically reacts with mouse CD41, a transmembrane glycoprotein also known as integrin alpha 2b GPIIb.
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Clone
    MWReg30
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD41 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Storage
    4 °C
    Storage Comment
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Target
    Integrin Alpha2b (CD41)
    Alternative Name
    CD41 (CD41 Products)
    Synonyms
    AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody
    Background
    The MWReg30 monoclonal antibody specifically reacts with mouse CD41, a transmembrane glycoprotein also known as integrin alpha 2b GPIIb. It is expressed on hematopoietic progenitors, megakaryocytes, and platelets. It forms a receptor with CD61 (integrin beta 3) that binds adhesion molecules such as fibrinogen, fibronectin, von Willebrand factor, and thrombin. Defects or absence of CD41 has been found to lead to coagulation disorders. The expression profile of CD150+,CD48-, and CD41- can be used to identify hematopoietic stem cells.
    Gene ID
    16399
    UniProt
    Q9QUM0
    Pathways
    Integrin Complex
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