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LILRB1 antibody (Alexa Fluor 647)
LILRB1
Reactivity: Human
FACS
Host: Mouse
Monoclonal
GHI-75
Alexa Fluor 647
Product Details anti-LILRB1 Antibody (Alexa Fluor 647)
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Target
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LILRB1
(Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))
Reactivity
All reactivities for LILRB1 antibodies
Human
Host
All hosts for LILRB1 antibodies
Mouse
Clonality
All clonalities for LILRB1 antibodies
Monoclonal
Conjugate
All conjugates for LILRB1 antibodies
This LILRB1 antibody is conjugated to Alexa Fluor 647
Application
All applications for LILRB1 antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
GHI-75
Isotype
IgG2b kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for LILRB1
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Target
LILRB1
(Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))
Alternative Name
CD85j (LILRB1 Products )
Synonyms
CD85J antibody, ILT-2 antibody, ILT2 antibody, LIR-1 antibody, LIR1 antibody, MIR-7 antibody, MIR7 antibody, leukocyte immunoglobulin like receptor B1 antibody, LILRB1 antibody
Background
CD85 is a group of Ig superfamily tansmembrane glycoproteins called Ig-Like Transcripts (ILTs) or Leukocyte Immunoglobulin-like Receptors (LIRs). CD85j is the 110kD member, known as ILT2, LIR1, or LILRB1, and MIR7. ILT2 structurally has four Ig domains and contains ITIMs in its cytoplasmic tail that provide inhibitory signals by recruiting SHP-1. ILT2 is found on the surface of B cells, plasma cells, dendritic cells, monocytes, subsets of NK and T cells. The ligands of ILT2 include a broad range of HLA-A, -B molecules, some HLA-C and HLA-G molecules, and the human cytomegalovirus UL18 protein.
Pathways
Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response
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