RGD1564516 antibody, MGC99322 antibody, TIMD4 antibody, B430010N18Rik antibody, TIM-4 antibody, Tim4 antibody, SMUCKLER antibody, TIM4 antibody, T-cell immunoglobulin and mucin domain containing 4 antibody, T-cell immunoglobulin and mucin domain containing 4 L homeolog antibody, T cell immunoglobulin and mucin domain containing 4 antibody, Timd4 antibody, TIMD4 antibody, timd4.L antibody
Background
Tim-4 is a transmembrane protein known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed on antigen-presenting cells and not on T cells. Tim-4 binds to Tim-1 to promote T cell proliferation by enhancing cell division and reducing apoptosis. Tim-4 bind to phosphatidylserine through its FG-CC' binding cleft in the N-terminal IgV domain to facilitate the clearance of apoptotic cells or bodies.