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CTLA4 antibody (APC)

CTLA4 Reactivity: Mouse WB, IHC, Neut, ICFC, ELISA (Capture) Host: Hamster Monoclonal UC10-4B9 APC
Catalog No. ABIN2658496
  • Target See all CTLA4 Antibodies
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Reactivity
    • 89
    • 57
    • 35
    • 5
    • 4
    Mouse
    Host
    • 59
    • 45
    • 13
    • 10
    • 1
    • 1
    Hamster
    Clonality
    • 72
    • 54
    • 2
    Monoclonal
    Conjugate
    • 59
    • 15
    • 13
    • 12
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTLA4 antibody is conjugated to APC
    Application
    • 78
    • 63
    • 51
    • 33
    • 17
    • 14
    • 13
    • 13
    • 10
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Neutralization (Neut), Intracellular Flow Cytometry (ICFC), ELISA (Capture)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    Clone
    UC10-4B9
    Isotype
    IgG
    Top Product
    Discover our top product CTLA4 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Alternative Name
    CD152 (CTLA4 Products)
    Synonyms
    CTLA-4 antibody, CTLA4 antibody, CD152 antibody, Cd152 antibody, Ctla-4 antibody, Ly-56 antibody, CD antibody, CELIAC3 antibody, GRD4 antibody, GSE antibody, IDDM12 antibody, sCTLA4 antibody, cytotoxic T-lymphocyte associated protein 4 antibody, cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA4 antibody, Ctla4 antibody
    Background
    CD152, also known as CTLA-4 or Ly-56, is a 33 kD member of the immunoglobulin superfamily. It is expressed on activated T and B lymphocytes. CD152 is similar to CD28 in amino acid sequence, structure, and genomic organization and these two receptors share common B7 family counter-receptors (B7-1, B7-2). Whereas CD28 delivers a costimulatory signal in T cell activation, CTLA-4 negatively regulates cell-mediated immune responses. CD152 is thought to play a role in the induction and maintenance of immunological tolerance as well as the development of protective immunity and thymocyte regulation.
    Pathways
    Cancer Immune Checkpoints
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