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Integrin Alpha2b antibody (APC)
CD41
Reactivity: Human
FACS, ELISA, IHC, IF
Host: Mouse
Monoclonal
HIP8
APC
Product Details anti-Integrin Alpha2b Antibody (APC)
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Target
See all Integrin Alpha2b (CD41) Antibodies
Integrin Alpha2b (CD41)
Reactivity
All reactivities for Integrin Alpha2b antibodies
Human
Host
All hosts for Integrin Alpha2b antibodies
Mouse
Clonality
All clonalities for Integrin Alpha2b antibodies
Monoclonal
Conjugate
All conjugates for Integrin Alpha2b antibodies
This Integrin Alpha2b antibody is conjugated to APC
Application
All applications for Integrin Alpha2b antibodies
Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
Cross-Reactivity
Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Capuchin Monkey
Purification
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
Clone
HIP8
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for Integrin Alpha2b
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Target
Integrin Alpha2b (CD41)
Alternative Name
CD41 (CD41 Products )
Synonyms
AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody
Background
CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, and thrombin.
Pathways
Integrin Complex
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