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MIF antibody (Biotin)
MIF
Reactivity: Human
BCA
Host: Mouse
Monoclonal
10C3
Biotin
Product Details anti-MIF Antibody (Biotin)
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Target
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MIF
(Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF))
Reactivity
All reactivities for MIF antibodies
Human
Host
All hosts for MIF antibodies
Mouse
Clonality
All clonalities for MIF antibodies
Monoclonal
Conjugate
All conjugates for MIF antibodies
This MIF antibody is conjugated to Biotin
Application
All applications for MIF antibodies
Biochemical Assay (BCA)
Purification
The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Clone
10C3
Isotype
IgG2b kappa
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for MIF
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Target
MIF
(Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF))
Alternative Name
MIF (MIF Products )
Synonyms
mif antibody, Mif antibody, gif antibody, glif antibody, mmif antibody, LOC100136498 antibody, LOC100284350 antibody, LOC100284546 antibody, GIF antibody, Glif antibody, GLIF antibody, MMIF antibody, macrophage migration inhibitory factor L homeolog antibody, macrophage migration inhibitory factor antibody, macrophage migration inhibitory factor (glycosylation-inhibiting factor) antibody, mif.L antibody, mif antibody, MIF antibody, Mif antibody, PHATRDRAFT_49660 antibody, LOC100136498 antibody, cl405_1 antibody, LOC100284546 antibody
Background
Human macrophage migration inhibitory factor (MIF) is a 12.5 kD, 115 amino acid, non-glycosylated polypeptide expressed by multiple cell types, including activated T cells, macrophages, eosinophils, epithelial cells, and endothelial cells. MIF plays many roles in biological processes such as catalytic activity, immunity, endocrine regulation, signal modulation, and inflammation. MIF is expressed in malignant cells including lung, liver, breast, colon, and prostate tumors. Studies suggest that MIF might serve as a molecular link between chronic inflammation and cancer. Recombinant MIF consists of a mixture of monomers, dimers, and trimers. The physiologically active forms are believed to be predominantly dimeric and trimeric forms.
Pathways
Regulation of Systemic Arterial Blood Pressure by Hormones , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Regulation of Carbohydrate Metabolic Process , Feeding Behaviour , Smooth Muscle Cell Migration , Negative Regulation of intrinsic apoptotic Signaling
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