IL2 antibody (Interleukin 2) (Pacific Blue)

Details for Product anti-IL2 Antibody No. ABIN2662352, Supplier: Log in to see
Antigen
  • IL2
  • IL-2
  • il2
  • TCGF
  • lymphokine
  • Il-2
  • POIL2
  • interleukin 2
  • IL2
  • il2
  • Il2
Alternatives
anti-Human IL2 antibody for Blocking Antibody
Reactivity
Human
481
248
98
31
17
10
6
6
5
4
3
3
1
1
Host
Rat
321
275
213
17
5
4
4
Clonality (Clone)
Monoclonal ()
Conjugate
This IL2 antibody is conjugated to Pacific Blue
89
51
51
28
21
18
17
14
12
11
9
8
8
7
7
7
7
7
7
7
6
6
6
4
4
4
4
4
4
4
3
3
2
2
1
1
1
Application
Flow Cytometry (FACS)
467
392
226
93
72
49
49
48
41
41
29
26
15
11
10
8
7
7
5
4
3
3
2
2
2
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Clone MQ1-17H12
Isotype IgG2a kappa
Cross-Reactivity Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Sooty mangabey (Cercocebus atys)
Purification The antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.
Alternative Name IL-2 (IL2 Antibody Abstract)
Background IL-2 is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells, promoting proliferation and maturation. Additionally, IL-2 has been found to stimulate growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes.
Research Area Cytokines, Immunology, Virology, Inflammation, Cancer
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.
Supplier Images
Flow Cytometry (FACS) image for anti-IL2 antibody (Interleukin 2)  (Pacific Blue) (ABIN2662352) anti-Interleukin 2 (IL2) antibody (Pacific Blue)
Flow Cytometry (FACS) image for anti-IL2 antibody (Interleukin 2)  (Pacific Blue) (ABIN2662352) anti-Interleukin 2 (IL2) antibody (Pacific Blue) (Image 2)
Background publications Dzhagalov, Chambon, He: "Regulation of CD8+ T lymphocyte effector function and macrophage inflammatory cytokine production by retinoic acid receptor gamma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 4, pp. 2113-21, 2007 (PubMed).

Raqib, Ekberg, Sharkar, Bardhan, Zychlinsky, Sansonetti, Andersson: "Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2." in: Infection and immunity, Vol. 70, Issue 6, pp. 3199-207, 2002 (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, 1996 (PubMed).

Andersson, Abrams, Björk, Funa, Litton, Agren, Andersson: "Concomitant in vivo production of 19 different cytokines in human tonsils." in: Immunology, Vol. 83, Issue 1, pp. 16-24, 1995 (PubMed).

Fernandez, Andersson, Andersson, Troye-Blomberg: "Cytokine synthesis analyzed at the single-cell level before and after revaccination with tetanus toxoid." in: European journal of immunology, Vol. 24, Issue 8, pp. 1808-15, 1994 (PubMed).

Skansén-Saphir, Andersson, Björk, Andersson: "Lymphokine production induced by streptococcal pyrogenic exotoxin-A is selectively down-regulated by pooled human IgG." in: European journal of immunology, Vol. 24, Issue 4, pp. 916-22, 1994 (PubMed).

Nisticò: "Communications among central nervous system, neuroendocrine and immune systems: interleukin-2." in: Progress in neurobiology, Vol. 40, Issue 4, pp. 463-75, 1993 (PubMed).

Taniguchi, Minami: "The IL-2/IL-2 receptor system: a current overview." in: Cell, Vol. 73, Issue 1, pp. 5-8, 1993 (PubMed).

Waldmann, Goldman, Top, Grant, Burton, Bamford, Roessler, Horak, Zaknoen, Kasten-Sportes: "The interleukin-2 receptor: a target for immunotherapy." in: Annals of the New York Academy of Sciences, Vol. 685, pp. 603-10, 1993 (PubMed).

Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, 1992 (PubMed).