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BCL6 antibody
BCL6
Reactivity: Human, Mouse
FACS
Host: Mouse
Monoclonal
IG191E-A8
unconjugated
Product Details anti-BCL6 Antibody
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Target
See all BCL6 Antibodies
BCL6
(B-Cell CLL/lymphoma 6 (BCL6))
Reactivity
All reactivities for BCL6 antibodies
Human, Mouse
Host
All hosts for BCL6 antibodies
Mouse
Clonality
All clonalities for BCL6 antibodies
Monoclonal
Conjugate
All conjugates for BCL6 antibodies
This BCL6 antibody is un-conjugated
Application
All applications for BCL6 antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Clone
IG191E-A8
Isotype
IgG1
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Discover our top product BCL6 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for BCL6
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Target
BCL6
(B-Cell CLL/lymphoma 6 (BCL6))
Alternative Name
Bcl-6 (BCL6 Products )
Synonyms
bcl5 antibody, laz3 antibody, bcl6a antibody, znf51 antibody, zbtb27 antibody, MGC132260 antibody, Bcl5 antibody, BCL5 antibody, BCL6A antibody, LAZ3 antibody, ZBTB27 antibody, ZNF51 antibody, B-cell CLL/lymphoma 6 L homeolog antibody, B-cell CLL/lymphoma 6 antibody, B cell leukemia/lymphoma 6 antibody, bcl6.L antibody, bcl6 antibody, BCL6 antibody, Bcl6 antibody
Background
B-cell lymphoma 6 (Bcl-6), is an 80 kD homodimer and member of the BTB-POZ zinc finger family. It consists of one BTB (POZ) domain and six C2H2-type zinc fingers. Bcl-6 is a transcriptional repressor as well as a master regulator of germinal center reaction. On B cells, Bcl-6 induces proliferation, antibody class switching and affinity maturation, while inhibits its differentiation to plasma cells. On T cells, Bcl-6 induces its differentiation to TFH. This molecule is also expressed in some B cell lymphomas and breast cancer cells.
Pathways
Chromatin Binding , Regulation of Leukocyte Mediated Immunity , Production of Molecular Mediator of Immune Response , Protein targeting to Nucleus
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