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C3AR1 antibody
C3AR1
Reactivity: Human
IHC, FACS
Host: Mouse
Monoclonal
hC3aRZ8
unconjugated
Product Details anti-C3AR1 Antibody
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Target
See all C3AR1 Antibodies
C3AR1
(Complement Component 3a Receptor 1 (C3AR1))
Reactivity
All reactivities for C3AR1 antibodies
Human
Host
All hosts for C3AR1 antibodies
Mouse
Clonality
All clonalities for C3AR1 antibodies
Monoclonal
Conjugate
All conjugates for C3AR1 antibodies
This C3AR1 antibody is un-conjugated
Application
All applications for C3AR1 antibodies
Immunohistochemistry (IHC), Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Clone
HC3aRZ8
Isotype
IgG2b
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for C3AR1
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Target
C3AR1
(Complement Component 3a Receptor 1 (C3AR1))
Alternative Name
C3AR (C3AR1 Products )
Synonyms
C3AR antibody, C3a-R antibody, c3ar1 antibody, AZ3B antibody, HNFAG09 antibody, C3a anaphylatoxin chemotactic receptor antibody, complement C3a receptor 1 antibody, complement component 3a receptor 1 antibody, c3ar1 antibody, C3AR1 antibody, C3ar1 antibody
Background
C3AR is a single chain protein of 482 aa, with seven membrane-spanning regions and a molecular weight of 54 Kd. C3AR is expressed by neutrophils, eosinophils, mast cells, monocytes, dendritic cells and there are reports of C3AR expression in non-immune cells such as hematopoietic and mesenchymal stem cells, epithelial and endothelial cells. C3AR is coupled to heterotrimeric G proteins and after C3a binding, the signal transduced, results in chemotaxis, granule enzyme release and superoxide anion production.
Pathways
Complement System
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