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EPH Receptor A2 antibody
EPHA2
Reactivity: Human
FACS, ICFC
Host: Mouse
Monoclonal
SHM16
unconjugated
Product Details anti-EPH Receptor A2 Antibody
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Target
See all EPH Receptor A2 (EPHA2) Antibodies
EPH Receptor A2 (EPHA2)
Reactivity
All reactivities for EPH Receptor A2 antibodies
Human
Host
All hosts for EPH Receptor A2 antibodies
Mouse
Clonality
All clonalities for EPH Receptor A2 antibodies
Monoclonal
Conjugate
All conjugates for EPH Receptor A2 antibodies
This EPH Receptor A2 antibody is un-conjugated
Application
All applications for EPH Receptor A2 antibodies
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
Purification
The antibody was purified by affinity chromatography.
Clone
SHM16
Isotype
IgG2b kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for EPH Receptor A2
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Target
EPH Receptor A2 (EPHA2)
Alternative Name
EphA2 (EPHA2 Products )
Synonyms
ARCC2 antibody, CTPA antibody, CTPP1 antibody, CTRCT6 antibody, ECK antibody, epha2 antibody, MGC89505 antibody, AW545284 antibody, Eck antibody, Myk2 antibody, Sek-2 antibody, Sek2 antibody, id:ibd5152 antibody, rtk6 antibody, G42 antibody, XE10 antibody, epha2-A antibody, EPH receptor A2 antibody, Eph receptor A2 antibody, epoxide hydrolase antibody, eph receptor A2 a antibody, EPH receptor A2 L homeolog antibody, EPHA2 antibody, Epha2 antibody, epha2 antibody, ephA2 antibody, epha2a antibody, epha2.L antibody
Background
Ephrin receptor A2 (EphA2), also known as Eck, is a 130 kD type I transmembrane glycoprotein which belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA2 is expressed on epithelial cells, keratinocytes, dendritic/Langerhans cells and melanocytes. It has also been observed in breast, cervical, ovarian, prostate, colon, skin and lung cancers. EphA2 is an oncoprotein which is an essential survival factor for many melanomas. EphA2 plays an important role in angiogenesis and tumor neovascularization through interaction with ephrin-A1, -A3, -A4 and -A5.
Pathways
RTK Signaling
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