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BID antibody
BID
Reactivity: Human
FACS
Host: Rat
Monoclonal
1H11
unconjugated
Product Details anti-BID Antibody
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Target
See all BID Antibodies
BID
(BH3 Interacting Domain Death Agonist (BID))
Reactivity
All reactivities for BID antibodies
Human
Host
All hosts for BID antibodies
Rat
Clonality
All clonalities for BID antibodies
Monoclonal
Conjugate
All conjugates for BID antibodies
This BID antibody is un-conjugated
Application
All applications for BID antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Clone
1H11
Isotype
IgG1
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Discover our top product BID Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
phosphate-buffered solution, pH 7.2, 0.09 % Sodium azide.
Storage
4 °C
Storage Comment
Upon receipt, store undiluted between 2°C and 8°C.
Target Details for BID
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Target
BID
(BH3 Interacting Domain Death Agonist (BID))
Alternative Name
BID (BID Products )
Synonyms
FP497 antibody, 2700049M22Rik antibody, AI875481 antibody, AU022477 antibody, BID antibody, bid antibody, si:ch211-238n5.6 antibody, fp497 antibody, xbid antibody, DKFZp469E066 antibody, BH3 interacting domain death agonist antibody, BH3 interacting domain death agonist S homeolog antibody, BID antibody, Bid antibody, bida antibody, bid.S antibody, bid antibody
Background
BID, a BH3 interacting domain death agonist is a member of the Bcl-2/Bcl-xL family. BID can form a heterodimer with either agonist BAX or antagonist Bcl-2. It is a mediator of mitochondrial damage induced by Caspase-8 (CASP8). After the cleavage by CASP8, the COOH-terminal part translocates to mitochondria and induces cytochrome c release, which in turn activates downstream caspases. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Pathways
Apoptosis , Caspase Cascade in Apoptosis , Positive Regulation of Endopeptidase Activity
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