PYCARD antibody (C-Term)
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- Target See all PYCARD Antibodies
- PYCARD (PYD and CARD Domain Containing (PYCARD))
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Binding Specificity
- C-Term
- Reactivity
- Human, Rat, Pig, Rabbit, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PYCARD antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ALIARVTNVE WLLDALYGKV LTDEQYQAVR AEPTNPSKMR KLFSFTPAWN
- Predicted Reactivity
- Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 86%, Rat: 79%
- Characteristics
- This is a rabbit polyclonal antibody against PYCARD. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human PYCARD
- Top Product
- Discover our top product PYCARD Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 195 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PYCARD (PYD and CARD Domain Containing (PYCARD))
- Alternative Name
- PYCARD (PYCARD Products)
- Synonyms
- ASC antibody, CARD5 antibody, TMS antibody, TMS-1 antibody, TMS1 antibody, 9130417A21Rik antibody, Asc antibody, TNS1 antibody, masc antibody, asc1 antibody, zAsc antibody, zgc:109874 antibody, PYD and CARD domain containing antibody, PYCARD antibody, Pycard antibody, pycard antibody
- Background
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Pycard is a cytosolic soluble protein that forms insoluble aggregates and enhances etoposide-induced apoptosis.
Alias Symbols: ASC, CARD5, MGC10332, TMS, TMS-1, TMS1
Protein Interaction Partner: PYCARD, EXOC5, SQSTM1, BECN1, UBC, RALB, IKBKB, CHUK, NLRP2, PYDC2, NLRP12, NLRP1, NLRC4, NLRP3, POP1, SRF, MEFV, PRKAR1A, CASP1,
Protein Size: 195 - Molecular Weight
- 21 kDa
- Gene ID
- 29108
- NCBI Accession
- NM_013258, NP_037390
- UniProt
- Q9ULZ3
- Pathways
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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