SMARCC1 antibody (C-Term)

Catalog No. ABIN2777854

Product Details anti-SMARCC1 Antibody

Target: SMARCC1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Rabbit, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMARCC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TKSEEKETEE NKELTDTCKE RESDTGKKKV EHEISEGNVA TAAAAALASA

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SMARCC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SMARCC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1105 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SMARCC1

Target: SMARCC1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1))

Alternative Name: SMARCC1 (SMARCC1 Products)

Synonyms: smarcc1 antibody, MGC53976 antibody, BAF155 antibody, CRACC1 antibody, Rsc8 antibody, SRG3 antibody, SWI3 antibody, AI115498 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 L homeolog antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 antibody, smarcc1.L antibody, smarcc1a antibody, SMARCC1 antibody, Smarcc1 antibody

Background: SMARCC1 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.
Alias Symbols: Rsc8, SRG3, SWI3, BAF155, CRACC1
Protein Interaction Partner: PLSCR1, OTX1, ADAMTSL4, BAZ1B, UBC, AURKB, WWOX, EED, RNF2, BMI1, ITCH, NEDD4, HDAC6, UL29, Dlg4, tat, EPAS1, VCP, NOTCH1, ARID1B, PHF10, KDM1A, SMARCA5, ARID1A, TOP2B, SMARCE1, SMARCD2, SMARCD1, SMARCC2, SMARCB1, SMARCA4, SMARCA2, SMARCA1, RBBP5, HDAC1,
Protein Size: 1105

Molecular Weight: 123 kDa

Gene ID: 6599

NCBI Accession: NM_003074, NP_003065

UniProt: Q92922

Pathways: Chromatin Binding