T-Box 5 antibody (Middle Region)
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- Target See all T-Box 5 (TBX5) Antibodies
- T-Box 5 (TBX5)
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This T-Box 5 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- RMQSKEYPVV PRSTVRQKVA SNHSPFSSES RALSTSSNLG SQYQCENGVS
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against TBX5. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TBX5
- Top Product
- Discover our top product TBX5 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 349 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- T-Box 5 (TBX5)
- Alternative Name
- TBX5 (TBX5 Products)
- Synonyms
- TBX5 antibody, tbx-5 antibody, xtbx-5 antibody, xtbx5 antibody, tbx5 antibody, HOS antibody, tbx5.1 antibody, zTbx5 antibody, zf-tbx5 antibody, T-box 5 antibody, T-box 5 L homeolog antibody, T-box 5a antibody, TBX5 antibody, tbx5 antibody, tbx5.L antibody, Tbx5 antibody, tbx5a antibody
- Background
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TBX5 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs.
Alias Symbols: HOS
Protein Interaction Partner: KDM6A, SMARCA4, KAT5, GATA4, NKX2-5,
Protein Size: 349 - Molecular Weight
- 39 kDa
- Gene ID
- 6910
- NCBI Accession
- NM_080718, NP_542449
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