Tryptophan Hydroxylase 2 antibody (N-Term)
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- Target See all Tryptophan Hydroxylase 2 (TPH2) Antibodies
- Tryptophan Hydroxylase 2 (TPH2)
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Tryptophan Hydroxylase 2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- REAATESGKT AVVFSLKNEV GGLVKALRLF QEKRVNMVHI ESRKSRRRSS
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 85%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against TPH2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TPH2
- Top Product
- Discover our top product TPH2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 490 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Synthesis of serotonin by a second tryptophan hydroxylase isoform." in: Science (New York, N.Y.), Vol. 299, Issue 5603, pp. 76, (2003) (PubMed).
: "
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Synthesis of serotonin by a second tryptophan hydroxylase isoform." in: Science (New York, N.Y.), Vol. 299, Issue 5603, pp. 76, (2003) (PubMed).
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- Target
- Tryptophan Hydroxylase 2 (TPH2)
- Alternative Name
- TPH2 (TPH2 Products)
- Synonyms
- ADHD7 antibody, NTPH antibody, Ntph antibody, tphR antibody, wu:fq15a04 antibody, AU043594 antibody, tryptophan hydroxylase 2 antibody, tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) antibody, TPH2 antibody, Tph2 antibody, tph2 antibody
- Background
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Tryptophan hydroxylase (TPH, EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.
Alias Symbols: NTPH, ADHD7
Protein Interaction Partner: UBC,
Protein Size: 490 - Molecular Weight
- 56 kDa
- Gene ID
- 121278
- NCBI Accession
- NM_173353, NP_775489
- UniProt
- Q8IWU9
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