NKX3-1 antibody (Middle Region)
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- Target See all NKX3-1 Antibodies
- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NKX3-1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- FSHQKYLSAP ERAHLAKNLK LTETQVKIWF QNRRYKTKRK QLSSELGDLE
- Predicted Reactivity
- Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against NKX3-1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human NKX3-1
- Top Product
- Discover our top product NKX3-1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 234 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
- Alternative Name
- NKX3-1 (NKX3-1 Products)
- Synonyms
- Xbagpipe antibody, Xbap antibody, bagpipe antibody, koza antibody, nkx3-1 antibody, nkx3.1 antibody, si:ch211-67o1.2 antibody, nkx3a antibody, MGC53041 antibody, MGC97890 antibody, Bax antibody, NKX3.1 antibody, NKX3A antibody, Nkx-3.1 antibody, BAPX2 antibody, NKX3 antibody, NK3 homeobox 1 L homeolog antibody, NK3 homeobox 1 antibody, NK-3 transcription factor, locus 1 (Drosophila) antibody, nkx3-1.L antibody, NKX3-1 antibody, nkx3-1 antibody, Nkx3-1 antibody
- Background
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The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BAPX2, NKX3, NKX3.1, NKX3A
Protein Interaction Partner: STRA13, CHPF, AEN, RABL6, TEX264, STMN3, LMCD1, SPDEF, CKAP4, HNRNPA0, CCT7, HMG20B, FEM1B, HSP90B1, TPT1, RPL37A, RARG, PTMS, PEBP1, ND4, MNAT1, MAN2B1, RPSA, TOP1, WDR77, TOPORS, KAT2B, SP5, SP4, SP3, SP2, SP1, HDAC1, HIPK2, SRF,
Protein Size: 234 - Molecular Weight
- 26 kDa
- Gene ID
- 4824
- NCBI Accession
- NM_006167, NP_006158
- UniProt
- Q99801
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
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