EPOR antibody (N-Term)
-
- Target See all EPOR Antibodies
- EPOR (Erythropoietin Receptor (EPOR))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Goat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This EPOR antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- DHLGASLWPQ VGSLCLLLAG AAWAPPPNLP DPKFESKAAL LAARGPEELL
- Predicted Reactivity
- Cow: 85%, Dog: 100%, Goat: 91%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against EPOR. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human EPOR
- Top Product
- Discover our top product EPOR Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 508 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- EPOR (Erythropoietin Receptor (EPOR))
- Alternative Name
- EPOR (EPOR Products)
- Synonyms
- EPOR antibody, epor antibody, EPO-R antibody, erythropoietin receptor antibody, erythropoietin receptor L homeolog antibody, EPOR antibody, epor antibody, Epor antibody, epor.L antibody
- Background
-
The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC138358, EPO-R
Protein Interaction Partner: PIK3R1, SRC, MST1R, JAK2, SH2B2, STAT5A, CBL, CRKL, GRB2, UBC, SOCS2, PLCG1, INPP5D, CISH, NOSIP, ATXN2L, GAB2, GAB1, GRAP, STAT5B, SOCS3, MAPK3, IRS2, SHC1, PLCG2, SYK, KITLG, GNB2L1, MAPK1, PTPN6, PTPN11, KLK3, LYN, KIT, VAV1, GNAI1, CSF2RB, EPOR, EPO,
Protein Size: 508 - Molecular Weight
- 53 kDa
- Gene ID
- 2057
- NCBI Accession
- NM_000121, NP_000112
- UniProt
- P19235
- Pathways
- JAK-STAT Signaling
-