ACVR1C/ALK7 antibody (N-Term)
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- Target See all ACVR1C/ALK7 (ACVR1C) Antibodies
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Pig, Dog, Rabbit, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ACVR1C/ALK7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QVFCHSSNNV TKTECCFTDF CNNITLHLPT ASPNAPKLGP MELAIIITVP
- Predicted Reactivity
- Cow: 100%, Dog: 83%, Guinea Pig: 80%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 81%, Rabbit: 100%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against ACVR1C. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACVR1C
- Top Product
- Discover our top product ACVR1C Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 493 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- Alternative Name
- ACVR1C (ACVR1C Products)
- Synonyms
- ACVRLK7 antibody, ALK7 antibody, Alk-7 antibody, C230097P10 antibody, Alk7 antibody, habrec1 antibody, activin A receptor type 1C antibody, activin A receptor, type IC antibody, ACVR1C antibody, Acvr1c antibody
- Background
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ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM].
Alias Symbols: ACVRLK7, ALK7
Protein Interaction Partner: HSP90AA1, TDGF1, INHBB,
Protein Size: 493 - Molecular Weight
- 55 kDa
- Gene ID
- 130399
- NCBI Accession
- NM_145259, NP_660302
- UniProt
- Q8NER5
- Pathways
- Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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