LOXL1 antibody (N-Term)
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- Target See all LOXL1 Antibodies
- LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LOXL1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RWRQLIQWEN NGQVYSLLNS GSEYVPAGPQ RSESSSRVLL AGAPQAQQRR
- Predicted Reactivity
- Cow: 83%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against LOXL1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human LOXL1
- Top Product
- Discover our top product LOXL1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 574 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice." in: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 35, Issue 11, pp. 1063-8, (2012) (PubMed).
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Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice." in: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 35, Issue 11, pp. 1063-8, (2012) (PubMed).
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- Target
- LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))
- Alternative Name
- LOXL1 (LOXL1 Products)
- Synonyms
- LOL antibody, LOXL antibody, Loxl antibody, si:ch211-238c15.1 antibody, lol antibody, loxl antibody, loxl-1 antibody, oxl-1 antibody, lysyl oxidase like 1 antibody, lysyl oxidase-like 1 antibody, lysyl oxidase like 1 L homeolog antibody, LOXL1 antibody, loxl1 antibody, Loxl1 antibody, loxl1.L antibody
- Background
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LOXL1 is a member of the lysyl oxidase family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LOL, LOXL
Protein Interaction Partner: ATXN1, CUL2, FBLN5, ELN,
Protein Size: 574 - Molecular Weight
- 53 kDa
- Gene ID
- 4016
- NCBI Accession
- NM_005576, NP_005567
- UniProt
- Q08397
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