POLL antibody (Middle Region)
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- Target See all POLL Antibodies
- POLL (Polymerase (DNA Directed), lambda (POLL))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Rat, Mouse, Rabbit, Cow, Guinea Pig, Dog, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POLL antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SLSEHALSTA VVRNTHGCKV GPGRVLPTPT EKDVFRLLGL PYREPAERDW
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 83%
- Characteristics
- This is a rabbit polyclonal antibody against POLL. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human POLL
- Top Product
- Discover our top product POLL Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 575 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- POLL (Polymerase (DNA Directed), lambda (POLL))
- Alternative Name
- POLL (POLL Products)
- Synonyms
- T10O24.13 antibody, T10O24_13 antibody, zgc:66320 antibody, zgc:77901 antibody, wu:fe49a04 antibody, beta-n antibody, pol-kappa antibody, BETAN antibody, POLKAPPA antibody, 1110003P06Rik antibody, AV007317 antibody, DNA polymerase lambda (POLL) antibody, DNA polymerase lambda antibody, polymerase (DNA directed), lambda antibody, polymerase (DNA) lambda antibody, Pol{lambda} antibody, PTRG_00468 antibody, poll antibody, POLL antibody, MCYG_03796 antibody, LOC9325878 antibody, MGYG_02138 antibody, Poll antibody
- Background
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POLL is a repair polymerase.It is involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Alias Symbols: BETA-N, FLJ46002, POL-KAPPA, BETAN, POLKAPPA
Protein Interaction Partner: KRTAP10-3, KRTAP10-7, FAM9B, KRT40, FSD2, SSX2IP, TFIP11, PNMA1, TFCP2, MAGEA12, TRIM23, APP, DCUN1D1, REV1, LDOC1, RPA1, PCNA, CDK2, UBE2H, UBE2E1, UBE2D3, UBE2D2, UBE2D1,
Protein Size: 575 - Molecular Weight
- 63 kDa
- Gene ID
- 27343
- NCBI Accession
- NM_013274, NP_037406
- UniProt
- Q9UGP5
- Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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