PSMB5 antibody (Middle Region)
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- Target See all PSMB5 Antibodies
- PSMB5 (Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMB5 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IVAADSRATA GAYIASQTVK KVIEINPYLL GTMAGGAADC SFWERLLARQ
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PSMB5. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PSMB5
- Top Product
- Discover our top product PSMB5 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 263 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- Target
- PSMB5 (Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5))
- Alternative Name
- PSMB5 (PSMB5 Products)
- Synonyms
- LMPX antibody, MB1 antibody, X antibody, etID309919.2 antibody, fb59c07 antibody, si:zc14a17.13 antibody, wu:fb59c07 antibody, x antibody, zgc:86820 antibody, proteasome subunit beta 5 antibody, proteasome (prosome, macropain) subunit, beta type 5 antibody, proteasome subunit beta 5 L homeolog antibody, proteasome (prosome, macropain) subunit, beta type, 5 antibody, PSMB5 antibody, psmb5 antibody, Psmb5 antibody, psmb5.L antibody
- Background
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB5 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit).The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LMPX, MB1, MGC104214, X
Protein Interaction Partner: UBC, AURKA, PSMD14, BMI1, PSMG3, PSMB8, PSMB7, PSMB6, PYCRL, AP3M1, RPP38, PSMB4, PSMB3, PSMB2, PSMB1, PSMA7, PSMA6, PSMA5, PSMA4, PSMA3, PSMA1, KIF5B, EPB41L1, CAST, XRN1, CDK20, CDKL1, PSMA2, PARK2, BAG3, IQCB1, HSP90AB1, HSP90AA1, FN1, IKBKAP, PSMA8, P
Protein Size: 263 - Molecular Weight
- 28 kDa
- Gene ID
- 5693
- NCBI Accession
- NM_002797, NP_002788
- UniProt
- P28074
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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