Cullin 4B antibody (C-Term)
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- Target See all Cullin 4B (CUL4B) Antibodies
- Cullin 4B (CUL4B)
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Horse, Rabbit, Cow, Guinea Pig, Goat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Cullin 4B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IQMKETVEEQ ASTTERVFQD RQYQIDAAIV RIMKMRKTLS HNLLVSEVYN
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Cul4b. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product CUL4B Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 970 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Cullin 4B (CUL4B)
- Alternative Name
- Cul4b (CUL4B Products)
- Synonyms
- MRXHF2 antibody, MRXS15 antibody, MRXSC antibody, SFM2 antibody, 2700050M05Rik antibody, AA409770 antibody, CUL-4B antibody, mKIAA0695 antibody, RGD1564494 antibody, im:7140950 antibody, im:7150765 antibody, MGC115611 antibody, Tb03.1J15.620 antibody, sfm2 antibody, mrxsc antibody, mrxhf2 antibody, cullin 4B antibody, cullin 4B S homeolog antibody, CUL4B antibody, Cul4b antibody, cul4b antibody, cul4b.S antibody, Tb927.3.1290 antibody
- Background
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Cul4b is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
Alias Symbols: 2700050M05Rik, AA409770, KIAA0695, mKIAA0695, CUL-4B
Protein Interaction Partner: Nedd8, Eed, Pou5f1,
Protein Size: 970 - Molecular Weight
- 111 kDa
- Gene ID
- 72584
- NCBI Accession
- NM_001110142, NP_001103612
- UniProt
- A2A432
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