Acrosin antibody (C-Term)
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- Target See all Acrosin (ACR) Antibodies
- Acrosin (ACR)
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Binding Specificity
- C-Term
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Reactivity
- Human, Cow, Horse, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Acrosin antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GKIDTCQGDS GGPLMCKDSK ESAYVVVGIT SWGVGCARAK RPGIYTATWP
- Predicted Reactivity
- Cow: 79%, Horse: 79%, Human: 100%, Sheep: 79%
- Characteristics
- This is a rabbit polyclonal antibody against ACR. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product ACR Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 421 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Acrosin (ACR)
- Alternative Name
- ACR (ACR Products)
- Synonyms
- ACR antibody, MGC130972 antibody, Acro antibody, Acrosin antibody, acrosin antibody, acrosin L homeolog antibody, acrosin prepropeptide antibody, ACR antibody, acr.L antibody, Acr antibody
- Background
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Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
Alias Symbols: -
Protein Interaction Partner: TP53BP1, SERPINA5, ZP3, ZP2, E2F4,
Protein Size: 421 - Molecular Weight
- 46 kDa
- Gene ID
- 49
- NCBI Accession
- NM_001097, NP_001088
- UniProt
- P10323
- Pathways
- cAMP Metabolic Process
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