Angiopoietin 1 antibody (N-Term)
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- Target See all Angiopoietin 1 (ANGPT1) Antibodies
- Angiopoietin 1 (ANGPT1)
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Angiopoietin 1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- FAFLAAILTH IGCSNQRRSP ENSGRRYNRI QHGQCAYTFI LPEHDGNCRE
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against ANGPT1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product ANGPT1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 498 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Angiopoietin 1 (ANGPT1)
- Alternative Name
- ANGPT1 (ANGPT1 Products)
- Synonyms
- AGP1 antibody, AGPT antibody, ANG1 antibody, 1110046O21Rik antibody, Ang-1 antibody, Ang1 antibody, Agpt antibody, Agpt1 antibody, ang1 antibody, wu:fc76g06 antibody, ANG-1 antibody, angpt1 antibody, MGC80788 antibody, angiopoietin 1 antibody, angiopoietin 1 S homeolog antibody, ANGPT1 antibody, Angpt1 antibody, angpt1 antibody, angpt1.S antibody
- Background
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Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: AGP1, AGPT, ANG1
Protein Interaction Partner: UBC, ANGPT2, ANGPT1, TEK, ITGA5,
Protein Size: 498 - Molecular Weight
- 55 kDa
- Gene ID
- 284
- NCBI Accession
- NM_001146, NP_001137
- UniProt
- Q15389
- Pathways
- RTK Signaling, Glycosaminoglycan Metabolic Process
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