SOS1 antibody (N-Term)

Catalog No. ABIN2789455

Product Details anti-SOS1 Antibody

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YFELLKQLEE KSEDQEDKEC MKQAITALLN VQSGMEKICS KSLAKRRLSE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Sos1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Sos1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOS1

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Alternative Name: Sos1 (SOS1 Products)

Target Type: Viral Protein

Background: Sos1 promotes the exchange of Ras-bound GDP by GTP.
Alias Symbols: 4430401P03Rik, 9630010N06, AI449023
Protein Interaction Partner: Egfr, Spry3, Spry4, Spry2, Spry1, Crkl, Nck1, Mapk1, Mapk3, Csf1r, Grb2, Crk, Fyn, Fgr, Src, Pik3r1, Ptpn6,
Protein Size: 1319

Molecular Weight: 151 kDa

Gene ID: 20662

NCBI Accession: NM_009231, NP_033257

UniProt: Q62245

Pathways: RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling